Vincent MacDermot RA was born in Montreal on June 14, 1957. He came to the United States as a child with his family in 1964 where they settled in Staten Island, New York.

Vincent MacDermot entered the architecture profession as a sole practitioner in 1987 after serving apprenticeships with architectural and engineering firms in Manhattan and Staten Island, including the office of Paul Rudolph RA, former dean of Architecture at Yale University, Tom Rochon RA, Joseph Pell Lombardi RA, Albert Melniker RA, and Alphonse Calvanico PE.

His practice provides residential, commercial and industrial design working with Staten Island and NYC clientele, including 20 years of providing marketing/rendering services to the Office of the Staten Island Borough President. Office projects include the Social Security Administration Building at Richmond Avenue, the CYO Center at Mount Loretto, the Headquarters for Seamen’s Society for Children and Families at 50 Bay Street, Offices for Caddell Drydock, Renderings for the Office of the Staten Island Borough President; the Closed Landfill, St. George Station, South Beach Fishing Pier, the New Boardwalk, Parks and Sports Fields, Education Complex in New Springville, renderings for Snug Harbor Cultural Center and Staten Island Botanical Gardens and a wide range of commercial and residential projects.

Vincent MacDermot received 55 awards for design from the Staten Island Chamber of Commerce, 1 from the American Institute of Architects and an award from the national competition 'Innovations in Housing'.

In 2009 Vincent MacDermot closed his architecture practice in order to represent his father, composer Galt MacDermot in the revival of HAIR on Broadway, in response to the Senior MacDermot who said 'take care of the music, take care of the men'. The Diane Paulus directed production went on to win the Tony Award for 'Best Revival' beating out 'West Side Story' and others. The revival on Broadway sparked 18 new productions around the world which continue presently. During the following 10 years he and his wife MaryAnne focused on the development and digital conversion of his father's music catalog to participate in and take advantage of the new streaming platforms; Spotify, Apple and Amazon and others. He made deals for publishing representation for his father's full catalog of over 1500 songs.

During this 10 year period he became a journeyman Local 40 Ironworker working on the World Trade Center; Tower 4, Tower 3 and the WTC Hub, The George Washington Bridge, Verrazzano Bridge and Bayonne Bridge, Columbia-Presbyterian Hospital York at 69th Street and the Chapin School at 84th Street.

In 2019 Vincent MacDermot returned to his architecture practice in the community of Staten Island.